Non-penetrance and late appearance of polyps in families with familial adenomatous polyposis
نویسندگان
چکیده
منابع مشابه
Non-penetrance and late appearance of polyps in families with familial adenomatous polyposis.
One case of non-penetrance of the familial adenomatous polyposis (FAP) gene at 59 years of age and late onset of polyps on endoscopy and biopsy in this and two other families is described. Screening protocols should include dental screening as well as indirect ophthalmoscopy and endoscopy to detect minimal manifestations of the gene. In the absence of a specific DNA predictive test, bowel scree...
متن کاملNon-penetrance and late appearance of polyps in families with familial adenomatous polyposis
Accepted for publication 2 February 1993 Abstract One case of non-penetrance of the familial adenomatous polyposis (FAP) gene at 59 years of age and late onset of polyps on endoscopy and biopsy in this and two other families is described. Screening protocols should include dental screening as well as indirect ophthalmoscopy and endoscopy to detect minimal manifestations of the gene. In the abse...
متن کاملPrevention and management of duodenal polyps in familial adenomatous polyposis.
Correspondence to: Mr L Brosens, Department of Pathology, Academic Medical Center, Meibergdreef 9, Amsterdam 1105 AZ, the Netherlands; l.a.brosens@ amc.uva.nl _________________________ F amilial adenomatous polyposis (FAP) is one of two well described forms of hereditary colorectal cancer. The primary cause of death from this syndrome is colorectal cancer which inevitably develops usually by th...
متن کاملNovel germline mutations in the adenomatous polyposis coli gene in Polish families with familial adenomatous polyposis.
A Plawski, J Lubiński, T Banasiewicz, J Paszkowski, D Lipinski, A Strembalska, G Kurzawski, T Byrski, S Zajaczek, D Hodorowicz-Zaniewska, T Gach, I Brozek, D Nowakowska, E Czkwaniec, P Krokowicz, M Drews, J Zeyland, W Juzwa, R Słomski . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ...
متن کاملA Preponderance of Polyps: Sequelae of Familial Adenomatous Polyposis
A man in his fourth decade with familial adenomatous polyposis (FAP) and previous colectomy due to colon adenocarcinoma underwent esophagogastroduodenoscopy (EGD) to investigate 3 days of nausea, epigastric abdominal pain, and coffee ground emesis; no source of bleeding was found. During the endoscopy, patchy mucosal abnormalities throughout the duodenum were identified and biopsied (Figure 1)....
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ژورنال
عنوان ژورنال: Gut
سال: 1994
ISSN: 0017-5749
DOI: 10.1136/gut.35.4.572-a